Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2
Loading...
Links to Files
Author/Creator ORCID
Date
2020-09-24
Type of Work
Department
Program
Citation of Original Publication
Tao Peng et al., Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2, Appl. Phys. Lett. 117, 120601 (2020); https://doi.org/10.1063/5.0021842
Rights
This item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Tao Peng et al., Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2, Appl. Phys. Lett. 117, 120601 (2020); https://doi.org/10.1063/5.0021842 and may be found at https://aip.scitation.org/doi/10.1063/5.0021842.
Access to this item will begin on 09/24/2021
This article may be downloaded for personal use only. Any other use requires prior permission of the author and AIP Publishing. This article appeared in Tao Peng et al., Enhancing sensitivity of lateral flow assay with application to SARS-CoV-2, Appl. Phys. Lett. 117, 120601 (2020); https://doi.org/10.1063/5.0021842 and may be found at https://aip.scitation.org/doi/10.1063/5.0021842.
Access to this item will begin on 09/24/2021
Subjects
Abstract
Lateral flow assay (LFA) has long been used as a biomarker detection technique. It has advantages such as low cost, rapid readout, portability, and ease of use. However, its qualitative readout process and lack of sensitivity are limiting factors. We report a photon-counting approach to accurately quantify LFAs while enhancing sensitivity. In particular, we demonstrate that the density of SARS-CoV-2 antibodies can be quantified and measured with an enhanced sensitivity using this simple laser optical analysis.