Improvements to the Deep Learning Classi?cation of Compton Camera Based Prompt Gamma Imaging for Proton Radiotherapy

dc.contributor.authorBasalyga, Jonathan N.
dc.contributor.authorBarajas, Carlos A.
dc.contributor.authorKroiz, Gerson C.
dc.contributor.authorGobbert, Matthias
dc.contributor.authorMaggi, Paul
dc.contributor.authorPolf, Jerimy
dc.date.accessioned2025-08-13T20:14:33Z
dc.date.issued2020
dc.description.abstractReal-time imaging has potential to greatly increase the e?ectiveness of proton beam therapy for cancer treatment. One promising method of real-time imaging is the use of a Compton camera to detect prompt gamma rays, which are emitted along the path of the beam, in order to reconstruct their origin. However, because of limitations in the Compton camera’s ability to detect prompt gammas, the data are often ambiguous, making reconstructions based on them unusable for practical purposes. Deep learning’s ability to detect subtleties in data that traditional models do not use make it one possible candidate for the improvement of classi?cation of Compton camera data. The base network can be made cheaper via reducing hidden layer count while maintaining comparable classi?cation performance. Additionally, even a simple training schedule can show improvements in the training process. Several variations of the network showed promise in their ability to classify multiple beam energies. However more improvements need to be made to the network for the performance on multiple beam energies to meet our goal of 90% classi?cation accuracy.
dc.description.sponsorshipThis work is supported by the grant “CyberTraining: DSE: Cross-Training of Researchers in Computing, Applied Mathematics and Atmospheric Sciences using Advanced Cyberinfrastructure Resources” from the National Science Foundation (grant no. OAC–1730250). The research reported in this publication was also supported by the National Institutes of Health National Cancer Institute under award number R01CA187416. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The hardware used in the computational studies is part of the UMBC High Performance Computing Facility (HPCF). The facility is supported by the U.S. National Science Foundation through the MRI program (grant nos. CNS–0821258, CNS–1228778, and OAC–1726023) and the SCREMS program (grant no. DMS–0821311), with additional substantial support from the University of Maryland, Baltimore County (UMBC). See hpcf.umbc.edu for more information on HPCF and the projects using its resources. Co-author Carlos Barajas additionally acknowledges support as HPCF RA.
dc.description.urihttps://hpcf-files.umbc.edu/research/papers/BasalygaBarajas_Summer2020.pdf
dc.format.extent28 pages
dc.genretechnical reports
dc.genrepreprints
dc.identifierdoi:10.13016/m26ktk-6ob4
dc.identifier.urihttp://hdl.handle.net/11603/39781
dc.language.isoen
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Mathematics and Statistics Department
dc.relation.ispartofUMBC Faculty Collection
dc.relation.ispartofUMBC Student Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.subjectUMBC High Performance Computing Facility (HPCF)
dc.titleImprovements to the Deep Learning Classi?cation of Compton Camera Based Prompt Gamma Imaging for Proton Radiotherapy
dc.typeText
dcterms.creatorhttps://orcid.org/0000-0003-1745-2292

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