PIK3CA GENE EDITING IN BREAST CANCER CELL LINES
| dc.contributor.author | Albalawy, Wafaa | |
| dc.contributor.department | Hood College Biology | |
| dc.contributor.program | Biomedical and Environmental Science | |
| dc.date.accessioned | 2024-09-09T12:44:25Z | |
| dc.date.available | 2024-09-09T12:44:25Z | |
| dc.date.issued | 2016-05 | |
| dc.description.abstract | This project is designed to show that mutations in PIK3CA gene cause some HER2+ breast cancer patients to not respond to Trastuzumab and Lapatinib therapy. Experimental design is to correct PIK3CA mutations in a collection of breast cancer cell lines by editing using CRISPR. The conformation of the hypothesis is based on regaining cell lines with edited PIK3CA sensitive to treatment. | |
| dc.format.extent | 45 pages | |
| dc.genre | Mock Grant Proposal | |
| dc.identifier | doi:10.13016/m2vzyw-xype | |
| dc.identifier.uri | http://hdl.handle.net/11603/36114 | |
| dc.language.iso | en_US | |
| dc.title | PIK3CA GENE EDITING IN BREAST CANCER CELL LINES | |
| dc.type | Text |