Synthesis of 2′-Deoxy-9-deaza Nucleosides Using Heck Methodology

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dc.contributor.authorTemburnikar, Kartik Waman
dc.contributor.authorBrace, Kelin
dc.contributor.authorSeley-Radtke, Katherine
dc.date.accessioned2025-07-30T19:22:44Z
dc.date.issued2013-06-27
dc.description.abstractDuring the synthesis of a series of 2′-deoxy-9-deaza nucleosides using Heck methodology, the necessity for a pyrrole protecting group was discovered. The results of this brief study revealed that the benzyloxymethyl (BOM) group proved optimal, and Heck coupling using Jeffery conditions increased the coupling yield significantly. The results are reported herein.
dc.description.urihttps://pubs.acs.org/doi/10.1021/jo400913k
dc.format.extent19 pages
dc.genrejournal articles
dc.genrepostprints
dc.identifierdoi:10.13016/m2xwbw-nong
dc.identifier.citationTemburnikar, Kartik, Kelin Brace, and Katherine L. Seley-Radtke. “Synthesis of 2′-Deoxy-9-Deaza Nucleosides Using Heck Methodology.” The Journal of Organic Chemistry 78, no. 14 (July 19, 2013): 7305–11. https://doi.org/10.1021/jo400913k.
dc.identifier.urihttps://doi.org/10.1021/jo400913k
dc.identifier.urihttp://hdl.handle.net/11603/39590
dc.language.isoen_US
dc.publisherACS
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Faculty Collection
dc.relation.ispartofUMBC Chemistry & Biochemistry Department
dc.relation.ispartofUMBC Student Collection
dc.rightsThis document is the Accepted Manuscript version of a Published Work that appeared in final form in The Journal of Organic Chemistry, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/jo400913k
dc.titleSynthesis of 2′-Deoxy-9-deaza Nucleosides Using Heck Methodology
dc.typeText
dcterms.creatorhttps://orcid.org/0000-0002-0154-3459

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