Olfactory Ensheathing Cells Promote Differentiation of Neural Stem Cells and Robust Neurite Extension

Thumbnail Image

Files

nihms642276.pdf (1.63 MB)

Links to Files

https://link.springer.com/article/10.1007/s12015-014-9539-7

Permanent Link

https://doi.org/10.1007/s12015-014-9539-7
 http://hdl.handle.net/11603/39054

Collections

UMBC Chemical, Biochemical & Environmental Engineering Department
UMBC College of Engineering and Information Technology Dean's Office
UMBC Faculty Collection

Author/Creator

Author/Creator ORCID

https://orcid.org/0000-0002-0644-744X

Date

2014-12-01

Type of Work

journal articles
postprints
Text

Department

Program

Citation of Original Publication

Sethi, Rosh, Roshan Sethi, Andy Redmond, and Erin Lavik. "Olfactory Ensheathing Cells Promote Differentiation of Neural Stem Cells and Robust Neurite Extension". Stem Cell Reviews and Reports 10, no. 6 (1 December 2014): 772–85. https://doi.org/10.1007/s12015-014-9539-7.

Rights

This version of the article has been accepted for publication, after peer review (when applicable) and is subject to Springer Nature’s AM terms of use, but is not the Version of Record and does not reflect post-acceptance improvements, or any corrections. The Version of Record is available online at: https://doi.org/10.1007/s12015-014-9539-7

Subjects

Neural progenitor
Paracrine signaling
Scaffold
Olfactory ensheathing glia
CNS injury
Tissue engineering

Abstract

The goal of this study was to gain insight into the signaling between olfactory ensheathing cells (OECs) and neural stem cells (NSCs). We sought to understand the impact of OECs on NSC differentiation and neurite extension and to begin to elucidate the factors involved in these interactions to provide new targets for therapeutic interventions.