Advancing Cell-Free Manufacturing: Challenges in Scale-up and Automation Workshop Report
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Author/Creator ORCID
Date
2024-11-20
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Program
Citation of Original Publication
Romantseva, Eugenia, Fernanda Piorino Macruz de Oliveira, Chad Sundberg, G. Sitta Sittampalam, and Elizabeth Strychalski. “Advancing Cell-Free Manufacturing: Challenges in Scale-up and Automation Workshop Report.” NIST, November 20, 2024. https://www.nist.gov/publications/advancing-cell-free-manufacturing-challenges-scale-and-automation-workshop-report.
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This is a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law.
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Public Domain
Subjects
Abstract
The National Institute of Standards and Technology (NIST) and the National Center for Advancing Translational Sciences (NCATS) convened the workshop Advancing Cell-free Manufacturing: Challenges in Scale-up and Automation in Rockville, Maryland in February 2024. This workshop brought together over fifty participants, representing the interests and needs of stakeholders in academic, industrial, and government settings. Together, through various plenary discussions, case studies, and working groups, participants broadly surveyed the field and focused on identifying both near-term and long-term needs to support cell-free expression systems. This report synthesizes the workshop discussion and presents actionable recommendations aimed at removing the remaining barriers to realizing the full impact of CFE systems on biomanufacturing and applications of biotechnology.