A Plasmodesmata-Localized Protein Mediates Crosstalk between Cell-to-Cell Communication and Innate Immunity in Arabidopsis

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https://academic.oup.com/plcell/article/23/9/3353/6097603

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https://doi.org/10.1105/tpc.111.087742
 http://hdl.handle.net/11603/28799

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UMBC Biological Sciences Department
UMBC Faculty Collection
UMBC Student Collection

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Author/Creator ORCID

https://orcid.org/0000-0002-7496-3200

Date

2011-09-20

Type of Work

journal articles
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Citation of Original Publication

Jung-Youn Lee and others, A Plasmodesmata-Localized Protein Mediates Crosstalk between Cell-to-Cell Communication and Innate Immunity in Arabidopsis, The Plant Cell, Volume 23, Issue 9, September 2011, Pages 3353–3373, https://doi.org/10.1105/tpc.111.087742

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Attribution 4.0 International (CC BY 4.0)

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Abstract

Plasmodesmata (PD) are thought to play a fundamental role in almost every aspect of plant life, including normal growth, physiology, and developmental responses. However, how specific signaling pathways integrate PD-mediated cell-to-cell communication is not well understood. Here, we present experimental evidence showing that the Arabidopsis thaliana plasmodesmata-located protein 5 (PDLP5; also known as HOPW1-1-INDUCED GENE1) mediates crosstalk between PD regulation and salicylic acid–dependent defense responses. PDLP5 was found to localize at the central region of PD channels and associate with PD pit fields, acting as an inhibitor to PD trafficking, potentially through its capacity to modulate PD callose deposition. As a regulator of PD, PDLP5 was also essential for conferring enhanced innate immunity against bacterial pathogens in a salicylic acid–dependent manner. Based on these findings, a model is proposed illustrating that the regulation of PD closure mediated by PDLP5 constitutes a crucial part of coordinated control of cell-to-cell communication and defense signaling.