A Plasmodesmata-Localized Protein Mediates Crosstalk between Cell-to-Cell Communication and Innate Immunity in Arabidopsis

dc.contributor.authorLee, Jung-Youn
dc.contributor.authorWang, Xu
dc.contributor.authorCui, Weier
dc.contributor.authorSager, Ross
dc.contributor.authorModla, Shannon
dc.contributor.authorCzymmek, Kirk
dc.contributor.authorZybaliov, Boris
dc.contributor.authorvan Wijk, Klaas
dc.contributor.authorZhang, Chong
dc.contributor.authorLu, Hua
dc.contributor.authorLakshmanan, Venkatachalam
dc.date.accessioned2023-07-19T20:42:16Z
dc.date.available2023-07-19T20:42:16Z
dc.date.issued2011-09-20
dc.description.abstractPlasmodesmata (PD) are thought to play a fundamental role in almost every aspect of plant life, including normal growth, physiology, and developmental responses. However, how specific signaling pathways integrate PD-mediated cell-to-cell communication is not well understood. Here, we present experimental evidence showing that the Arabidopsis thaliana plasmodesmata-located protein 5 (PDLP5; also known as HOPW1-1-INDUCED GENE1) mediates crosstalk between PD regulation and salicylic acid–dependent defense responses. PDLP5 was found to localize at the central region of PD channels and associate with PD pit fields, acting as an inhibitor to PD trafficking, potentially through its capacity to modulate PD callose deposition. As a regulator of PD, PDLP5 was also essential for conferring enhanced innate immunity against bacterial pathogens in a salicylic acid–dependent manner. Based on these findings, a model is proposed illustrating that the regulation of PD closure mediated by PDLP5 constitutes a crucial part of coordinated control of cell-to-cell communication and defense signaling.en_US
dc.description.sponsorshipWe thank B.-C. Yoo for helpful discussions and comments on the manuscript, J. Sherrier for helpful suggestions on TEM techniques, A. Maule for sharing unpublished information and helpful comments, W. Park for cloning PDLP5-GFP, X. Dong for npr1 seeds, N. Chua for pER8 plasmid, J. Caplan for assisting with confocal imaging and providing GV3101 cells carrying TMV-GFP and p19, M. Gilbertson for providing CMV, and L. Crozier and S. Kitto for proofreading. Publically available Arabidopsis mutant lines were obtained from ABRC. The funds supporting this work were provided by the National Science Foundation (IOS 0954931), the National Institutes of Health (COBRE P20 RR15588), the University of Delaware Research Initiative Strategic Initiative Program to J.-Y.L., and the University of Maryland Baltimore County (a start-up fund) and National Science Foundation (RIG-0818651) to H.L.en_US
dc.description.urihttps://academic.oup.com/plcell/article/23/9/3353/6097603en_US
dc.format.extent21 pagesen_US
dc.genrejournal articlesen_US
dc.identifierdoi:10.13016/m2ysw9-7tlw
dc.identifier.citationJung-Youn Lee and others, A Plasmodesmata-Localized Protein Mediates Crosstalk between Cell-to-Cell Communication and Innate Immunity in Arabidopsis, The Plant Cell, Volume 23, Issue 9, September 2011, Pages 3353–3373, https://doi.org/10.1105/tpc.111.087742en_US
dc.identifier.urihttps://doi.org/10.1105/tpc.111.087742
dc.identifier.urihttp://hdl.handle.net/11603/28799
dc.language.isoen_USen_US
dc.publisherOxford University Pressen_US
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Biological Sciences Department Collection
dc.relation.ispartofUMBC Faculty Collection
dc.relation.ispartofUMBC Student Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.en_US
dc.rightsAttribution 4.0 International (CC BY 4.0)*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.titleA Plasmodesmata-Localized Protein Mediates Crosstalk between Cell-to-Cell Communication and Innate Immunity in Arabidopsisen_US
dc.typeTexten_US
dcterms.creatorhttps://orcid.org/0000-0002-7496-3200en_US

Files

Original bundle

Now showing 1 - 2 of 2
Loading...
Thumbnail Image
Name:
plcell_v23_9_3353.pdf
Size:
3.33 MB
Format:
Adobe Portable Document Format
Description:
Main article
Loading...
Thumbnail Image
Name:
plcell_v23_9_3353_s1.zip
Size:
5.28 MB
Format:
Unknown data format
Description:
Additional files

License bundle

Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
license.txt
Size:
2.56 KB
Format:
Item-specific license agreed upon to submission
Description: