THE ROLE OF IN VITRO COMBINATION EFFICACY EVALUATION TO PRIORITIZE ANTI-HIV COMPOUNDS FOR CLINICAL TRIALS
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Hood College Biology
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Biomedical and Environmental Science
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Abstract
The major goal of this thesis project was to determine the role of in vitro
combination efficacy to help prioritize compounds for clinical trials. So many compounds
are available and currently in development that some method is needed to establish
priority for compound use. The results of this study indicate that a potentially useful
tool for prioritizing compounds for clinical trials has been developed using an in vitro
combination assay technique.