GENERATION OF A MUTANT FLY TO EVALUATE THE IN VIVO ROLE OF PA-PLA1 IN DROSOPHILA
| dc.contributor.author | Balagatte, Sanchitha G. | |
| dc.date.accessioned | 2024-09-09T13:36:35Z | |
| dc.date.available | 2024-09-09T13:36:35Z | |
| dc.date.issued | 2006-04 | |
| dc.description.abstract | Our long term goal is to understand how proteins mediate, in vivo, the complex interrelationship between the lipid metabolism and membrane bending , in relavence to fission and fusion of vesicles. Phospholipases constitute a diverse group of enzymes involved in metabolism of the phosphoglycerolipids and generate second messengers for a number of different signaling pathways and also has a role in intracelluluar membrane trafficking and vesicular transport (6). Our main focus of the study is to evaluate the in vivo role of phosphatidic specific phospholipase Al (PA-PLA1) enzyme in Drosophila.The specific objective of the study is to generate tools such as Drosophila PA-PLA1 specific antibody and a mutant to study the in vivo role of PA-PLA1. | |
| dc.format.extent | 17 pages | |
| dc.genre | Mock Grant Proposal | |
| dc.identifier | doi:10.13016/m2rp1h-ee3b | |
| dc.identifier.uri | http://hdl.handle.net/11603/36119 | |
| dc.language.iso | en_US | |
| dc.title | GENERATION OF A MUTANT FLY TO EVALUATE THE IN VIVO ROLE OF PA-PLA1 IN DROSOPHILA | |
| dc.type | Text |