Exploring Deep Learning to Improve Compton Camera Based Prompt Gamma Image Reconstruction for Proton Radiotherapy

dc.contributor.authorKroiz, Gerson C.
dc.contributor.authorBarajas, Carlos A.
dc.contributor.authorGobbert, Matthias K.
dc.contributor.authorPolf, Jerimy C.
dc.date.accessioned2021-05-21T16:52:08Z
dc.date.available2021-05-21T16:52:08Z
dc.date.issued2021
dc.description.abstractProton beam radiotherapy is a cancer treatment method that uses proton beams to irradiate cancerous tissue while simultaneously sparing doses to healthy tissue. In order to optimize radiational doses to the tumor and ensure that healthy tissue is spared, many researchers have suggested verifying the treatment delivery through real-time imaging. One promising method of real-time imaging is through a Compton camera, which can image prompt gamma rays emitted along the beam’s path through the patient. However, the reconstructed images are often noisy and unusable for verifying proton treatment delivery due to limitations with the camera. We present the usage of deep learning to remove and correct the various problems that exist within our data.en_US
dc.description.sponsorshipThis work is supported by the National Institutes of Health National Cancer Institute under award number R01CA187416. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The hardware used in the computational studies is part of the UMBC High Performance Computing Facility (HPCF). The facility is supported by the U.S. National Science Foundation through the MRI program (grant nos. CNS–0821258, CNS–1228778, and OAC–1726023) and the SCREMS program (grant no. DMS–0821311), with additional substantial support from the University of Maryland, Baltimore County (UMBC). See https://hpcf.umbc.edu for more information on HPCF and the projects using its resources.en_US
dc.description.urihttp://hpcf-files.umbc.edu/research/papers/Kroiz_ICDATA2021.pdfen_US
dc.format.extent4 pagesen_US
dc.genreconference papers and proceedingsen_US
dc.genrepostprints
dc.identifierdoi:10.13016/m2qgs1-itid
dc.identifier.citationGerson C. Kroiz, Carlos A. Barajas, Matthias K. Gobbert, and Jerimy C. Polf. Exploring Deep Learning to Improve Compton Camera Based Prompt Gamma Image Reconstruction for Proton Radiotherapy. In: The 17th International Conference on Data Science (ICDATA’21), accepted (2021). (HPCF machines used: taki.).en_US
dc.identifier.urihttp://hdl.handle.net/11603/21594
dc.language.isoen_USen_US
dc.publisherSpringer
dc.relation.isAvailableAtThe University of Maryland, Baltimore County (UMBC)
dc.relation.ispartofUMBC Mathematics Department Collection
dc.relation.ispartofUMBC Faculty Collection
dc.relation.ispartofUMBC Student Collection
dc.rightsThis item is likely protected under Title 17 of the U.S. Copyright Law. Unless on a Creative Commons license, for uses protected by Copyright Law, contact the copyright holder or the author.
dc.subjectUMBC High Performance Computing Facility (HPCF)en_US
dc.titleExploring Deep Learning to Improve Compton Camera Based Prompt Gamma Image Reconstruction for Proton Radiotherapyen_US
dc.typeTexten_US
dcterms.creatorhttps://orcid.org/0000-0003-1745-2292

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