Polyurethane Nanocapsules Incorporating Epigallocatechin Gallate, A Green Tea Extract

Date

2025-02-26

Department

Program

Citation of Original Publication

Ale, Temitope, Nhyira Ghunney, Narendra Pandala, Budd Tucker, Kassandra McFadden, Jack Hutcheson, and Erin Lavik. "Polyurethane Nanocapsules Incorporating Epigallocatechin Gallate, A Green Tea Extract." Advanced NanoBiomed Research. (February 26, 2025): 2400204. https://doi.org/10.1002/anbr.202400204.

Rights

This work was written as part of one of the author's official duties as an Employee of the United States Government and is therefore a work of the United States Government. In accordance with 17 U.S.C. 105, no copyright protection is available for such works under U.S. Law.
Public Domain

Abstract

Explosions cause 79% of combat-related injuries, often leading to traumatic brain injury (TBI) and hemorrhage. Epigallocatechin gallate (EGCG), a green tea polyphenol, aids neuroprotection and wound healing. In this work, we sought to investigate the fabrication and characterization of polyurethane nanocapsules encapsulating EGCG, demonstrating controlled, on-demand release, and highlighting their potential for targeted therapeutic delivery in trauma care.