COMPARISON OF LABORATORY CONTAMINATION THROUGH OPEN AND CLOSED DOORS IN A MODEL SYSTEM
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Hood College Biology
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Biomedical and Environmental Science
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Abstract
The results of this research demonstrate that with corridors at a
higher air pressure than adjoining rooms, rooms with open doors
receive greater contamination than rooms with closed doors. Examination
of the data by an analysis of variance (ANOVA), employing
a significance level of 0.05, yielded a P value of 4.9 x 10¯¹² for
the effect of door condition. The average contamination level for
test rooms with open doors was four times greater than that for
test rooms with closed doors. Diffusion and local air turbulence
in the corridor are probably responsible for the greater contamination
of rooms with open doors.
With doors closed, increasing the pressure differential significantly
increased test room contamination. The closed door P value
for the effect of pressure differential was 7.3 x 10¯⁹. When room
doors were closed, increasing the pressure differential from 0.005
to 0.02 inches of water doubled the average test room contamination.
With doors open, the pressure differential had much less significance
than with doors closed. The open door P value for the
effect of pressure differential was 0.046.
Location of test rooms, relative to source room, affected their
contamination levels in both open and closed door experiments.
This occurred because the swing of the source room door resulted in
a directional distribution of tracer which affected the rooms differently.
