• Spatial alterations of De Novo purine biosynthetic enzymes by Akt-independent PDK1 signaling pathways 

  Schmitt, Danielle L.; Sundaram, Anand; Jeon, Miji; Luu, Bao Tran; An, Songon (PLOS ONE, 2018)

  A macromolecular complex of the enzymes involved in human de novo purine biosynthesis, the purinosome, has been shown to consist of a core assembly to regulate the metabolic activity of the pathway. However, it remains ...

• The role of the C-domain of bacteriophage T4 gene 32 protein in ssDNA binding and dsDNA helix-destabilization: Kinetic, single-molecule, and cross-linking studies 

  Pant, Kiran; Anderson, Brian; Perdana, Hendrik; Malinowski, Matthew; Win, Aye T.; Pabst, Christopher; Williams, Mark C.; Karpel, Richard L. (PLOS ONE, 2018)

  The model single-stranded DNA binding protein of bacteriophage T4, gene 32 protein (gp32) has well-established roles in DNA replication, recombination, and repair. gp32 is a single-chain polypeptide consisting of three ...

• A Mathematical Model for Enzyme Clustering in Glucose Metabolism 

  Jeon, Miji; Hye-Won, Kang; An, Songon (Nature, 2017)

  We have recently demonstrated that the rate-limiting enzymes in human glucose metabolism organize into cytoplasmic clusters to form a multienzyme complex, the glucosome, in at least three different sizes. Quantitative ...

• Awareness, Analysis, and Action: Curricular Alignment for Student Success in General Chemistry 

  Jewett, Sarah; Sutphin, Kathy; Gierasch, Tiffany; Hamilton, Pauline; Lilly, Kathleen; Miller, Kristine; Newlin, Donald; Pires, Richard; Sherer, Maureen; LaCourse, William R. (ACS Publications, 2018)

  This article examines the ways that a shared faculty experience across five partner institutions led to a deep awareness of the curriculum and pedagogy of general chemistry coursework, and ultimately, to a collaborative ...

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