EVALUATION OF SEVERAL ANAEROBIC MARINE BACTERIA FOR THE PRODUCTION OF NOVEL BIOACTIVE COMPOUNDS
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Hood College Biology
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Biomedical and Environmental Science
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Abstract
Cultures of anaerobic marine bacteria belonging to the genera
Desulfovibrio and Spirochaeta were isolated from their natural environment and
evaluated for the production of bioactive metabolites. The extracts from
cultures of nine isolates were tested on bioassays including antibacterial,
antifungal, anti-AIDS, genotoxic and antineoplastic bioassay systems. Several
extracts from cultures of isolates of Desulfovibrio spp. exhibited antibacterial
activity against Gram positive bacteria. This activity was due to a nonpolar
constituent of the spent culture medium.