DEVELOPMENT, VALIDATION, AND APPLICATION OF A QUANTITIVE REAL-TIME POLYMERASE CHAIN REACTION ASSAY FOR HUMAN T CELL LEUKEMIA VIRUS DNA
| dc.contributor.author | Miley, Wendell J. | |
| dc.contributor.department | Hood College Biology | |
| dc.contributor.program | Biomedical and Environmental Science | |
| dc.date.accessioned | 2024-03-11T14:54:49Z | |
| dc.date.available | 2024-03-11T14:54:49Z | |
| dc.date.issued | 2000-12 | |
| dc.description.abstract | A PCR assay to measure HTLV-I/II proviral DNA was developed, validated, and applied to test a hypothesis relevant to HTLV associated disease pathogenesis. Due to the potential for functional interaction between HTLV-I/II and HIV regulatory proteins, HTLV-I/II provirus load might be expected to be higher in HTLV-I/II/HIV co-infected subjects compared to HTLV-I/II singly infected subjects. However, analysis of HTLV- I/II provirus load in 37 co-infected and 105 singly infected subjects did not show a significant difference in HTLV-I/II provirus load (p = 0.35) even when HTLV-I/II provirus load was adjusted for age and gender. | |
| dc.format.extent | 181 pages | |
| dc.genre | Thesis (M.S.) | |
| dc.identifier | doi:10.13016/m2nbtz-txgu | |
| dc.identifier.uri | http://hdl.handle.net/11603/31909 | |
| dc.language.iso | en_US | |
| dc.title | DEVELOPMENT, VALIDATION, AND APPLICATION OF A QUANTITIVE REAL-TIME POLYMERASE CHAIN REACTION ASSAY FOR HUMAN T CELL LEUKEMIA VIRUS DNA | |
| dc.type | Text |