Identifying Telomere Repeat Change During Exercise Using Electric Pulse Stimulation

Abstract

This project aims to discover a link between the reduced telomere length shortening and exercise. Human skeletal muscle cell (HSkMC) will be exposed to various treatment conditions and electric pulse stimulation to replicate the effects of exercise. Quantification of telomere length will be done by the use of TELOTAGGGTM. This project will help determine which metabolic conditions and/or if reactive oxygen species (ROS) impact the lengths of telomere repeats in HSkMC. This will help to determine if these factors are related to telomeres and exercise.