Wireless bipotentiostat circuit for glucose and H2O2 interrogation

Abstract

Here we present a cost-effective point-of-use wireless platform for the electrochemical detection of low concentrations of glucose and hydrogen peroxide (H2O2) simultaneously. The electrochemical system utilizes a dual sensor integrated with a portable bipotentiostat. The bipotentiostat hardware implements a basic design that reduces the cost of construction and increases the affordability of the instrument, while providing similar functionality to the more expensive bench-top potentiostats. The bipotentiostat utilizes inexpensive components, common Ag/AgCl reference and platinum counter electrodes, two working electrodes, and it is designed to detect currents within the range of 20 uA to 7 mA. Additionally, the bipotentiostat is integrated with wireless module ESP8266 that interfaces with a smartphone to enable real-time monitoring and visualization of the analyte concentration levels. The results show that the self-designed bipotentiostat is capable of performing chronoamperometry and demonstrate an electrochemical detection system that is a portable alternative system for laboratory and point-of-use testing.