ROLE OF INDOLEAMINE 2,3-DIOXYGENASE 2 IN NON-HODGKIN LYMPHOMA

Author/Creator

Author/Creator ORCID

Date

2017-12

Department

Hood College Biology

Program

Biomedical and Environmental Science

Citation of Original Publication

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Subjects

Abstract

The intent of this proposal is to utilize the rate-limiting catabolism of tryptophan to determine its level of involvement in protein expression as it relates to anti-tumor responses through genetic expression studies and cytokine recruitment assays. Exploring specific cytokine involvement as it relates to lymphomas will contribute a better underlying understanding of the enzyme indoleamine 2, 3-dioxygenase 2 (IDO2) and its involvement in disease development.